Cholesterol and Health

February 23, 2009

If you don’t know about, you oughta. He’s on my blogroll and I highly recommend all his materials as a source.

Recently, he interviewed Chris Masterjohn ( who offered as complete and concise an understanding of cholesterol that I’ve had the pleasure to encounter. It’s over an hour, but by the end of the hour, you’ll be in the 99th percentile of cholesterol knowledge.

Did you know there are the myriad functions of cholesterol in the body?

Did you know that LDL and HDL are not ‘cholesterol,’ but lipoprotiens (Low Density Lipoprotein and High Density Lipoprotein) which are merely the vehicle that delivers cholesterol (and many other fat-soluble nutrients like vitamin K) to your cells?

Did you know the majority of cholesterol in your body is in your brain and adequate cholesterol is needed for optimal brain function?

Did you know cholesterol is a precursor to all sex hormones (progesterone, testosterone, estrogens) and is required for optimal circulating levels of these hormones?

Did you know cholesterol is essential for the synthesis of vitamin D?

Did you know there is no ‘good’ cholesterol or ‘bad’ cholesterol – just cholesterol.

Did you know the real hazard is not the level of LDL in the blood but the level of oxidized LDL. Oxidized LDL is not able to bind with the LDL receptors in the liver inhibiting the ability of the liver to to internalize the LDL.

Did you know to ask your doctor to test for pattern size in your LDL and LDL:HDL ratio (total ‘cholesterol’ is essentially meaningless for most of us)? Small, dense LDL is much more prone to oxidation and more easily penetrates the arterial wall and result in a plaque deposits.

Did you know that while statin drugs inhibit cholesterol synthesis in the liver (probably ‘OK’) that such drugs might also inhibit cholesterol synthesis in other vital organs like, say, the brain?!? (see previous paragraph on cholesterol and the brain)

Did you know statins also have the effect of depleting the vital antioxidant Co Enzyme Q10 – lower concentrations of which are correlated with heart disease?

Believe it or not, there is a lot more covered in this interview. It’s a real keeper:


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